We are down to the round of 16 at the Winston-Salem Open and with the combination of withdrawals and upsets, the title is up for grabs.

John Isner and Tomas Berdych both pulled out of the tournament on Monday due to injuries. They are two of the top 15 players in the world and last years finalists.

Meanwhile on the court, 2nd seeded Andreas Seppi fell in the round of 32.

There are a number of players capable of winning the tournament with Tommy Robredo holding the honors of being the highest ranked player left in the field, at 22nd. But what is left are 10 players who are ranked from 22nd to 43rd in the World. This is a recipe for extremely competitive matches ahead.

A couple of competitors besides Robredo to keep an eye on include Gaels Monfils. The Frenchman would certainly be ranked higher if not for inactivity due to injury that dropped him from a ranking in the top 10 of the World. He is still making his comeback from the knee injury and looks to be very close to being all the way back. On the court, he certainly looks to be playing at a much higher level than 43rd in the world.

Alexandr Dolgopolov came into last years Winston-Salem Open as a player everyone wanted to see. At that time, the 24 year old look destined to break into the top 10. He sniffed it last year rising to 13th in the world but has struggled in 2013 and has watched his ranking slip to 38th in the world. Dolgopolov is a dangerous player with a lot of shots in his bag and a very solid serve.

Sam Querrey has to feel good about where he is in the tournament. The hard courts suit his game and with his big serve and crowd support behind him, he will be dangerous. Querrey has not won a title since 2012 in Los Angeles on the hard courts.

Dmitry Tursunov has had a solid summer and the veteran has defeated 4th ranked David Ferrer as recently as Cincinnati.

Whoever is left standing when the dust settles in Winston-Salem will be riding a huge wave of momentum into next weeks U.S. Open.